@v_47 You will want to make use of Bot’s command line interface, but you will effectively only be able to “push” data into the project files, rather than have Templater “watch” and “pull” data into the project file. See this thread to learn more about the differences. With the CLI, you can run Templater against any data set and any template simply by changing the templater-options.json file each time you invoke the CLI.
Alternatively, you could make use of the special aep column header in your sheet to switch between project files on a per-row basis, but when Bot is in “pull” mode, it watches a single data source. This means that multiple sheets would need to be pulled into a master sheet. Obviously this get a bit unwieldy. In that case, you could forgo the idea of a spreadsheet, and setup some kind of server that responded with JSON object arrays — each object in an array could have a different set of properties that would match to the various layers from different AEP files.
Please let us know if you have any further questions.